Oxygen-18 with enrichment more than 98% & nbsp;
|
& Nbsp; CAS number |
Isotope enrichment & nbsp; |
Molar weight |
|
14314-42-2 |
≥ 98% |
20.02 |
Oxygen-18 enriched water is used as a target, which is bombarded with a cyclotron or linear accelerator to produce Fluorine-18. Fluorine-18 is synthesized in 2-deoxy-2-18F-β-D-glucopyranose (18F-FDG), which is a radio-labeled sugar molecule used in PET (Positron Emission Tomography) imaging to locate abnormal glucose metabolism and localize many types tumors. Today 18F-FDG is the most widespread and successful PET radiopharmaceutical. 18F-FDG is an analogue of glucose, it is administered in vivo, and then 18F-FDG is transported from blood to tissues in a similar way to glucose. Cells take up FDG like glucose, but it cannot be metabolized. A very important advantage of FDG-PET is that it helps to accurately determine the stage and foci of disease recurrence in many types of cancer.